The FDA approved BiG001 phase I trial for open tibial fracture has enrolled the 1^st subject in 2022 Jan. BiG001 is the combination device containing Osteo-Inductive Factor.
ClinicalTrial.gov Info:  https://clinicaltrials.gov/ct2/show/study/NCT04960722?cond=open+tibial+fracture&draw=2&rank=2